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艾美捷科技代理Innovotech品牌全系列产品


Innovotech公司专注于抗菌及生物膜解决方案领域。公司在标准化和定制化研究领域拥有卓越业绩,始终致力于满足客户需求。Innovotech的合同研究服务涵盖全周期:从早期问题识别与"抗生物膜活性"制剂筛选,到符合监管机构要求的产品宣称验证研究,再到用于营销推广的上市后产品比对研究。公司常规开发客户定制化体外模型作为研究起点,支持多维度测试参数的全面检测。

Innovotech的研发体系主要建立在两大专利技术平台:MBEC检测法®(最小生物膜根除浓度测定)和BEST检测法™(生物膜表观生存力检测)。基于这些平台,公司已开发出系列独特检测方法,适用于医疗、牙科、农业及工业领域中各类溶液态抗菌剂与表面涂层抗菌剂的测试。公司还融合平台技术与生物膜、医疗器械及银化学等领域的专业知识,开发出自有抗生物膜产品线:InnovoSIL™系列在医疗器械应用领域展现显著潜力,AgreGuard™-1在农业应用测试中验证卓越效力。Innovotech已构建测试平台的生物膜问题涉及导管及植入式医疗器械、抗生素药物研发、伤口愈合管理、特种涂料与防护涂层、水系统抗菌解决方案、牙科治疗及供水管线抗菌方案、农作物细菌/真菌病害防治、食品加工硬表面消毒剂等领域。


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Innovotech产品列表


品名产品描述货号
MBEC Assay® Biofilm Inoculator with Trough Base & Cellulose Coated PegsThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. This MBEC Assay® Biofilm Inoculator consists of a plastic lid with 96 cellulose-coated pegs and a trough base. One of its recommended uses is with plant pathogens.10/cs:19193;25/cs:19191;100/cs:19192
MBEC Assay® Biofilm Inoculator with 96 Well Base & Cellulose Coated PegsThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. This MBEC Assay® Biofilm Inoculator consists of a plastic lid with 96 cellulose-coated pegs and a well base. One of its recommended uses is with plant pathogens.10/cs:19173;25/cs:19171;100/cs:19172
MBEC Assay® Biofilm Inoculator with Trough Base & Titanium Dioxide Coated PegsThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. The MBEC Assay® Biofilm Inoculator consists of a plastic lid with a Titanium Dioxide coated well base.10/cs:19163;25/cs:19161;100/cs:19162
MBEC Assay® Biofilm Inoculator with 96 Well Base & Titanium Dioxide Coated PegsThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. The MBEC Assay® Biofilm Inoculator consists of a plastic lid with 96 Titanium Dioxide coated pegs and a well base.10/cs:19153;25/cs:19151;100/cs:19152
MBEC Assay® Biofilm Inoculator with Trough Base & Hydroxyapatite Coated PegsThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. The MBEC Assay® Biofilm Inoculator consists of a plastic lid with a Hydroxyapatite coated a well base.10/cs:19143;25/cs:19141;100/cs:19142
MBEC Assay® Biofilm Inoculator with 96 Well Base & Hydroxyapatite Coated PegsThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. The MBEC Assay® Biofilm Inoculator consists of a plastic lid with 96 Hydroxyapatite coated pegs and a well base.10/cs:19133;25/cs:19131;100/cs:19132
MBEC Assay® Biofilm Inoculator with Trough BaseThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. The MBEC Assay® Biofilm Inoculator consists of a plastic lid with a trough base.10/cs:19123;25/cs:19121;100/cs:19122
MBEC Assay® Biofilm Inoculator with 96 Well BaseThe MBEC Assay® Biofilm Inoculator is a high throughput screening assay used to determine the efficacy of antimicrobials against biofilms of a variety of microorganisms. The MBEC Assay® Biofilm Inoculator consists of a plastic lid with 96 pegs well base.10/cs:19113;25/cs:19111;100/cs:19112
InnovoSIL™-1 silverThe InnovoSIL™ family consists of novel antimicrobial silver complexes. InnovoSIL™-1 Antimicrobial Silver is ideally suited to coating onto or incorporating into medical devices, and is ready for testing.-
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艾美捷科技代理Tropic Marin品牌全系列产品


Tropic Marin公司于1964年在德国威斯巴登创立,凭借其丰富的海盐、矿物质混合物、细菌添加剂、测试套件和过滤设备产品线,Tropic Marin®为全球50多个国家的初学者、经验丰富的水族爱好者、动物园、大型水族馆、大学和实验室提供产品。


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▎Tropic Marin产品线

海盐系列

①PRO-REEF 珊瑚盐:高钙镁配方,促进硬骨珊瑚生长,稳定pH值,适用礁岩生态缸。

②BIO-ACTIF 活菌盐:添加天然生物聚合物与益生菌,增强生物抗病力,优化微生物平衡。

③经典海盐:含天然海水70种微量元素,医药级纯度,无硝酸盐/磷酸盐残留。

④溶解性:实验室验证的高溶解度,调配后比重精准匹配天然海水(1.024–1.026)。


补充剂与养护产品

TRACE-TRACE B 元素:针对珊瑚显色与健康的微量元素补充剂。

NP-BACTO 系列:包含平衡剂(Balance)和生物滤材(Tricks),通过益生菌降解硝酸盐/磷酸盐,维护水质6。

PRO-CORAL专业线:涵盖钙添加剂(BIO-CALCIUM)、碘补充剂(IODINE)及浮游生物粮(ZOOTON/PHYTON)。


Tropic Marin产品列表

品名规格货号
A- Elements200 ml ;500 ml ;1000 ml24104 ;24123;24113
All-For-Reef250 ml ;500 ml ;1000 ml;800g ;1600g26702 ; 26704 ;26706 ;26752;26754
Amino-Organic250 ml25104
Bio-Actif 海盐4 kg;10 kg;12.5 kg;20 kg;25kg10304;10310;10312;10320;10325
Bio-Actif Reactor 50005 L53105
Bio-Magnesium450 g;1500 g;1000 ml29402;29432;29454
Bio-Strontium200 g29002
Block Iodine1000 ml28890
Block Molydbenum1000 ml28892
Block Nickel1000 ml28894
Block Strontium1000 ml28896
Block Zinc1000 ml28898
Barium250 ml28830
Boron500 ml28860
Bromine500 ml28862
Calcium500 ml28864
Carbonate500 ml28866
Chromium250 ml28832
Cobalt250 ml28834
Copper250 ml28836
Fluorine500 ml28868
Iodine250 ml28838
Iron250 ml28840
Lithium250 ml28842
Magnesium500 ml28870
Manganese250 ml28844
Molybdenum250 ml28846
Nickel250 ml28848
Nitrogen500 ml28872
Phosphate500 ml28874
Potassium500 ml28876;24005
Rubidium250 ml28850
Selenium250 ml28852
Strontium500 ml28878
Sulfur500 ml28880
Vanadium250 ml28854
Tinc250 ml28854
Carbo-Calcium500 ml;1000 ml;700 g;1400 g26202;26204;26252;26254
Carbon400 g25604
Ca / Mg ProCa/Mg-Test Professional;Refill Pack28380;28790
Classic 海盐2 kg;4 kg;10 kg;12.5 kg;20 kg;25 kg10112 ;10124;10128;10130;10132;10130
Compact LabCompact Lab28500
Coral Clean250 ml24332
Cyo-Control500 ml24354
Elimi-Phos Rapid500 ml25354
Elimi-NP50 ml;250 ml24422;24424
Immuvit60 g24822
Elimi-Phos100 g;200 g;400 g;1,5 kg25404;25414、25304;25424;25314
K+ Elements200 ml ;500 ml ;1000 ml24204;24223;24213
Fiji Meerwasser20升10020
KH Pro TestKH-Test28784
lod50 ml24304
KH TestKH-Test  ;Refill Pack28240;28776
K+ Pro TestK+ Test Professional ;Refill Pack28390;28792
Lipo-Garlic50 ml24812
Liquid Buffer500 ml;1000 ml27062;27064
Nitribiotic25 ml ;50 ml27202;27204
Lipovit50 ml24802
NO2/NO3NO2/NO3-Test;Refill Pack28260 ;28780
NH4+/NHs TestNH4+/NH3-Test;Refill Pack28270;28782
NP-Bacto-Pellets500 ml ;1000 ml25702;25706
NO2/ NO3 Pro TestNO2/NO3-Test Professional;Refill Pack28360;28788
NP-Bacto-Tricks2000 ml;5000 ml;10000 ml25724;25726;25728
NP-Bacto-Balance500 ml;1000 ml24403;24405
O-Megavital CBD60 g24862
O-Megavital Nori17 g24871
Original Balling Components1 kg;3 x 1 kgA:26522;B:26524;C :26526;Set ABC:26528
pH testpH-Test saltwater;Refill Pack saltwater ;pH-Test freshwater ;Refill Pack freshwater28210;28770;28220;28772
Phos-Start75 g24462
Phos-Feed300 g24474
Phyton60 g24622
Phytonic50 ml;250 ml24652;24654
Plus NP250 ml24454
PO4 ProPO4-Test  Professional;Refill Pack28350 ;28786
PO4 TestPO4-Test;Refill Pack28250 ;28778
Potassium500 ml28876;24005
Pro-Coral Mineral250 g25002
Pro-Reef2 kg;4 kg;10 kg;12.5 kg;20 kg;25 kg10522;10524;10551;10560;10572;10581
Pro-Tect1000 ml24094
Professional LabCompact Lab28500
Reef Actif60 g24702
Reef Snow60 g24722
Syn-Biotic4 kg;10 kg;12.5 kg;20 kg;25kg10404;10410;10412;10420;10425
Triple Buffer250 g;1800 g27002;27052
Zooton60 g24602
Zootonic50 ml;250 ml24632 ;24634



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艾美捷科技代理Protein Ark品牌产品。


Protein Ark公司提供全流程的样品制备产品、分离试剂盒和定制服务,以协助用户开展从克隆到蛋白质以及从肽到抗体的研究。


产品范围包括:

(1)DNA电泳:Elite DNA分子量标准,Elite琼脂糖片;

(2)蛋白表达试剂:培养基优化试剂盒™,Dream™ Overnight SelenoMet Expression Media,IPTG,TCEP;

(3)蛋白纯化缓冲液:缓冲液,标准裂解、结合、洗涤和洗脱缓冲液,FLAG肽;

(4)亲和层析填料:用于抗体纯化的蛋白A和蛋白G,固定化金属亲和层析(IMAC),Fastback Ni Advance填料,GST和肝素亲和层析填料;

(5)IEX层析树脂:离子交换树脂;

(6)HIC层析填料:HIC培养基通常在中高盐浓度下结合;

(7)活化层析填料:具有多种偶联化学成分的各种活化培养基,可高效、快速、轻松、安全地固定各种功能配体;

(8)Annex病毒纯化层析填料:Annex VP系列层析介质具有薄的多孔惰性外壳,可排除分子量分别为>5000kDa、>700kDa、>400kDa的分子;

(9)内毒素清除树脂:用于去除特定内毒素的NoEndo™树脂,NoEndoTM试剂盒;

(10)Proteus离心柱试剂盒:Proteus蛋白A和G、Ni-IMAC试剂盒;

(11)Proteus洗涤剂交换迷你离心柱;

(12)预填充色谱柱:HiFliQ FPLC色谱柱;

(13)定制色谱柱填料:色谱柱硬件足够坚固,可进行多次使用和原位清洗,并且价格合理,可用作实验室规模、生物工艺和GMP应用的一次性色谱柱;

(14)体积排除柱

(15)空纯化柱:Proteus 一步批处理离心柱,Proteus FliQ FPLC Columns;

(16)样品制备:Proteus Mini 澄清离心柱;

(17)浓缩:变形杆菌X-微调器超滤浓缩器;

(18)蛋白质电泳:实时染色,Elite预染蛋白分子量标准,Eco预染蛋白质分子量标准;

(19)快速考马斯蛋白染色;

(20)蛋白质印迹底物。

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艾美捷科技代理DNA Polymerase Technology品牌全系列产品


DNA Polymerase Technology的核心领域是PCR(聚合酶链式反应),致力于通过先进的转基因酶和其他PCR产品,克服多个领域中的常见障碍,包括临床诊断、法医分析、食品安全、环境中病原体检测以及一般分子生物学研究。Klentaq公司发明的新型酶进一步提升了PCR性能,具有以下特点:扩增更长的目标片段,具有更高的保真度,反应速度更快,并且能够耐受血液或土壤等抑制性污染物。该公司产品线包括:Klentaq产品、OmniTaq产品、ZipTaq产品、 Long &Accurate 的产品、热启动产品、热启动LA产品、Lyoph-Ready产品、PCR增强剂和缓冲液、PCR试剂盒以及组合产品。此外,公司开发的其他技术还包括:PCR增强剂组合以及热启动缓冲液。


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DNA Polymerase Technology公司产品线

● Klentaq 产品:5-核酸外切酶缺陷型 Taq 聚合酶可提供更高的保真度和热稳定性,特别是作为 LA(长准确)酶混合物的一部分。Klentag1是 Jag DNA 聚合酶的 Klenow 片段类似物。它是已知最耐热的 Tag 形式,完全不具备核酸外切酶或内切酶活性,并且其晶体结构已被解析清楚。该酶的 LA版本是 Klentag1 和校对酶的混合物。


品名货号规格
Klentag1100100 ul (2,000 X25 ul rxns up to1kb)
Omni Klentag340125 ul (500 x 25ul rxns)
Omni Klentag2342125 ul (500 x 25ul rxns)
Omni Klentag C280100 ul (2,000 X25 ul rxns)
Omni Klentag AC240100 ul (2,000 X25 ul rxns)
Omni Klentag-S105100 ul (2,000 X25 ul rxns up to1 kb)


● OmniTag 产品:Klentaq的抗抑制DNA聚合酶经过特殊筛选,对多种常见的高效PCR抑制剂(例如:全血、血清、血浆、尿液、腐殖酸、胆盐、植物组织提取物、各类食品相关抑制剂、GITC(异硫氰酸胍)、乙醇等)具有极强的耐受性。因此,这些酶能在大多数市售Taq产品完全失效的抑制剂浓度下,依然进行有效的PCR扩增。Taq突变体的这一独特优势使得对多种临床样本、环境样本和法医样本进行免提取直接PCR成为可能,跳过了耗时的DNA提取步骤。

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品名货号规格
OmniTag300125 ul(500 X25 ul rxns)
OmniTaq 2302125 ul(500 X25 ul rxns)
OmniTag 2T302T250 rxns
OmniTag 3303125 ul(500 X25 ul rxns)


● ZipTaq产品

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品名货号规格
ZipTaq304125 ul (500 X 25 ul rxns)


●  Long &Accurate 产品:使用 DNA 聚合酶和校对酶的专利组合,具有更高的保真度,是扩增长片段DNA目标序列的理想选择,此外,它们通常具备更强的稳健性,因此扩增短片段目标序列时同样适用。


品名货号规格
Klentag LA110100 ul (2,000 X25 ul rxns up to1 kb)
OmniTag LA310125 ul(500 X25 ul rxns)
OmniTag 2LA312125 ul (500 X25 ul rxns)
OmniTag 3LA313125 ul (500 X25 ul rxns)
ZipTag LA314125 ul(500 X25 ul rxns)
Omni KlentagLA350125 ul(500 X25 ul rxns)
Omni Klentag2 LA344125 ul (500 X25 ul rxns)
CesiumKlentag C LA290100 ul(2,000 X25 ul rxns)
CesiumKlentag ACLA250100 ul (2,000 X25 ul rxns)
CesiumTad210100 ul(2,000 X25 ul rxns)
Klentaq-S LA115100 ul(2,000 X25 ul rxns)


●  Klentaq的热启动技术包含:

①铯酶:它们是Taq或 Klentaq1 DNA聚合酶的双重冷敏感突变体,由于在低温下活性受到抑制,它们能为PCR提供自动热启动

②适配体抑制技术:适用于所有酶,在低于循环温度时,该适配体形成发夹结构并结合到聚合酶的活性位点,从而使酶失活并防止错误扩增

③LA产品:具有更高的保真度以及更强的稳健性


品名货号规格
Hot Start Klentaq1HS100100 ul (2,000 X 25 ul rxns up to 1kb)
Hot Start OmniTaqHS300125 ul (500 x 25 ul rxns)
Hot Start OmniTaq 2HS302125 ul (500 X 25 ul rxns)
Hot Start OmniTaq 3HS303125 ul (500 X 25 ul rxns)
Hot Start ZipTaqHS304125 ul (500 X 25 ul rxns)
Hot Start Omni KlentaqHS340125 ul (500 X 25 ul rxns)
Hot Start Omni Klentaq 2HS342125 ul (500 X 25 ul rxns)
Hot Start Cesium Klentaq CHS280100ul (2000 x 25ul rxns)
Hot Start Cesium Klentaq ACHS240100ul (2000 x 25ul rxns)
CesiumTaq200100 ul (2,000 X 25 ul rxns)
Hot Start CesiumTaqHS200100 ul (2,000 X 25 ul rxns)
Hot Start Klentaq-SHS105100 ul (2,000 X 25 ul rxns up to 1kb)
RockStart Buffer SystemRock100100 rxns
Hot Start Klentaq LAHS110100 ul(2,000X 25 ul rxnsup to 1kb)
Hot Start OmniTaq LAHS310125 ul(500 x25 ul rxns)
Hot Start OmniTag 2 LAHS312125 ul (500 X25 ul rxns)
Hot Start OmniTag 3 LAHS313125 ul(500 X25 ul rxns)
Hot Start ZipTaq LAHS314125 ul(500 X25 ul rxns)
Hot Start Omni KlentagLAHS350125 ul(500 X25 ul rxns)
Hot Start Omni Klentag2 LAHS344125 ul(500 X25 ul rxns)
Hot Start CesiumKlentag C LAHS290100ul(2000 x25ul rxns)
Hot Start Cesium Klentag AC LAHS250100ul(2000 x25ul rxns)
Hot Start CesiumTag LAHS210100 ul (2,000X 25 ul rxns)

●  Lyoph-Ready 产品

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品名货号规格
Klentag LA110100 ul (2,000 X25 ul rxns up to1 kb)
OmniTag LA310125 ul(500 X25 ul rxns)
OmniTag 2LA312125 ul (500 X25 ul rxns)
OmniTag 3LA313125 ul (500 X25 ul rxns)
ZipTag LA314125 ul(500 X25 ul rxns)
Omni KlentagLA350125 ul(500 X25 ul rxns)
Omni Klentag2 LA344125 ul (500 X25 ul rxns)
CesiumKlentag C LA290100 ul(2,000 X25 ul rxns)
CesiumKlentag ACLA250100 ul (2,000 X25 ul rxns)
CesiumTad210100 ul(2,000 X25 ul rxns)
Klentaq-S LA115100 ul(2,000 X25 ul rxns)


●  PCR相关产品

①PCR增强剂和缓冲液产品:PEC 产品是非甜菜碱基 PCR 增强剂,专门设计用于抑制性模板。强烈建议将它们与我们的抑制抗性 Taq 和Klentag 突变体一起使用。它们还与大多数市售 DNA 聚合酶兼容。

②PCR 试剂盒产品:试剂盒包括 DNA 聚合酶、缓冲液和 dNTP,有标准套件和长而精确(LA) 套件。

③组合产品:测试多种酶和 PCR 增强剂混合物以优化 PCR 的一种经济高效的方法


品名货号规格
PCR Enhancer Cocktail 1E6006.25 ml(for 500rxns of 25ul each)
PCR Enhancer Cocktail 2E6206.25 ml(for 500rxns of 25ul each)
PCR Enhancer Cocktail 1 GCE6106.25 ml(for 500rxns of 25ul each)
PCR Enhancer Cocktail 2 GCE6306.25 ml(for 500rxns of 25ul each)
PCR Enhancer Cocktail PE6506.25 ml(for 500rxns of 25ul each)
5M BetaineEBET5 x 1.25ml
RockStartBuffer SystemRock100100 rxns
10x Klentag1Reaction BufferpH 9.2RB203 ml
10x Klentag1Reaction BufferpH 7.9RB213 ml
10x KlentagMutant ReactionBufferRB103 ml
10x Tag MutantReaction BufferRB303 ml
10x RT-LAMPReaction BufferRB403 ml
10x ZipTaqReaction BufferRB603 ml
10x Klentag-SReaction BufferRB703 ml
Storage/DilutionBufferSB3ml
5x Klentag1 PCR Kit120500 x 25 ul rxns
5x Klentag LA PCR Kit130500 x 25 ul rxns
5x Hot Start Klentag1 PCR KitHS120500 x25 ul rxns
5x OmniTag PCR Kit320500 x 25 ul rxns
5x omniTag LA PCR Kit330500 x25 ul rxns
5x Hot Start omniTag PCR KitHS320500 x 25 ul rxns
5x OmniTag 2 PCR Kit322500 X 25 ul rxns
5x OmniTag 2 LA PCR Kit332500 X 25 ul rxns
5x Hot Start omniTag 2 PCR KitHS322500 x25 ul rxns
5x OmniTag 3 PCR Kit323500 X 25 ul rxns
5x OmniTag 3 LA PCR Kit333500 X 25 ul rxns
5x Hot Start OmniTag 3 PCR KitHS323500 x25 ul rxns
5x ZipTaq PCR Kit324500 x25 ul rxns
5x Hot Start ZipTag KitHS324500 x 25 ul rxns
5x Omni Klentag PCR Kit360500 X 25 ul rxns
5x Omni Klentag LA PCR Kit370500 X 25 ul rxns
5x Hot Start Omni Klentag PCR KitHS360500 x25 ul rxns
5x omni Klentag 2 PCR Kit362500 X 25 ul rxns
5x Omni Klentag 2 LA PCR Kit372500 X 25 ul rxns
5x Hot Start Omni Klentag 2 PCR KitHS362500 x25 ul rxns
5x Cesium Klentag C PCR Kit2852,000 x 25 ul rxns
5x Cesium Klentag C LA PCR Kit2952,000 x 25 ul rxns
5x Hot Start Cesium Klentag CPCR KitHS2852,000 x 25 ul rxns
5x Cesium Klentag AC PCR Kit2602.000 x 25 urxns
5x Cesium Klentag AC LA PCR Kit2702.000 x 25 urxns
5x Hot Start Cesium Klentag AC PCR KitHS2602,000 x25 urxns
5x CesiumTag PCR Kit2202,000 x 25 urxns
5x CesiumTag LA PCR Kit2302,000 x25 ulrxns
5x Hot Start CesiumTag PCR KitHS2202.000 x25 urxns
5x Klentag-S PCR Kit125500 x25ul rxns
Enzyme combo500variable
Enzyme Combo LA510variable
Hot Start Enzyme ComboHS500variable
Hot Start Enzyme Combo LAHS510variable
PCR Enhancer Cocktail ComboE6401.25 ml eachenhancer


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艾美捷科技代理Gene Tools品牌


Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。


Morpholino介绍

Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。

Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:

● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;

● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;

● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;

● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。

配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

Gene Tools代理.png


Gene Tools公司产品介绍

● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。

● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。

● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。


产品名称Short DescriptionOligo sequenceSKU
Standard Control Oligo Negative control oligoCCTCTTACCTCAGTTACAATTTATAPCO-StandardControl-100
Vivo-Morpholino Standard Control OligoNegative Vivo-Morpholino control oligoCCTCTTACCTCAGTTACAATTTATAPCO-VivoStandardControl-100
Random Control Oligo 25-N25-base random sequence mixtureNNNNNNNNNNNNNNNNNNNNNNNNNPCO-RandomControl-25N-100
Zebrafish p53 oligoDanio rerio apoptosis suppression oligoGCGCCATTGCTTTGCAAGAATTGPCO-ZebrafishP53-100
Zebrafish Chordin Positive Control OligoDanio rerio Chordin positive control oligoATCCACAGCAGCCCCTCCATCATCCPCO-ZebrafishChordin-100-F
Clawed Frog Beta Catenin Positive Control OligoXenopus laevis Beta Catenin antisense oligoTTTCAACCGTTTCCAAAGAACCAGGPCO-BetaCatenin-100-F
Green Fluorescent Protein Positive ControlTranslation blocker for GFP targetACAGCTCCTCGCCCTTGCTCACCATPCO-GFPControl-100
Vivo-Morpholino GFP Positive ControlTranslation blocker for GFP target (Vivo-Morpholino)ACAGCTCCTCGCCCTTGCTCACCATPCO-VivoGFPControl-100
Fluoresceinated Vivo-Morpholino Std ControlNegative Vivo-Morpholino control oligo with 5'FluoresceinCCTCTTACCTCAGTTACAATTTATAPCO-FluorVivoStandardControl-100-F


● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。



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艾美捷科技代理Schircks Laboratories品牌。

瑞士Schircks Laboratories由B.Schircks博士于1980年创立,主要生产蝶啶及蝶啶类化合物(Pteridines)。至今,Schircks实验室合成了100多种蝶啶类化合物,主要用于科学研究和临床诊断应用。产品包括:

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11.1806-(L-1,2,3-Trihydroxybutyl)-pterin [Rhamnopterin]
11.182(6R,S)-5,6,7,8-Tetrahydro-L-rhamnopterin dihydrochloride
11.203L-Biopterin [L-erythro-Biopterin] 
11.2067,8-Dihydro-L-biopterin
11.209(6R,S)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride 
11.212(6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride
11.213(6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride
11.215(6S)-5,6,7,8-Tetrahydro-L-biopterin sulfate
11.216(6S)-5,6,7,8-Tetrahydro-L-biopterin sulfate
11.217(6R)-5-Methyl-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
11.218D-Biopterin [D-erythro-Biopterin]
11.220(6R,S)-5,6,7,8-Tetrahydro-D-biopterin dihydrochloride
11.221D-threo-Biopterin [Dictyopterin] 
11.223(6R,S)-5,6,7,8-Tetrahydro-D-threo-biopterin dihydrochloride 
11.228Deoxysepiapterin
11.2296-((1R,S)-Hydroxypropyl)pterin [(1'R,S)-2'-Deoxybiopterin]
11.2317-Biopterin 
11.2347-Tetrahydro-L-biopterin dihydrochloride
11.260Oncopterin
11.2704-Hydroxy-6-(L-erythro-1,2-dihydroxy-propyl)-2-(methylthio)pteridine
11.2804-Amino-L-biopterin [2,4-Diamino-6-(L-erythro-1',2'-dihydroxypropyl)pteridine]
11.2824-Amino-(6R,S)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
11.2834-Amino-(6R)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
11.303D-Neopterin [D-erythro-Neopterin] 
11.3067,8-Dihydro-D-neopterin  
11.3077,8-Dihydro-D-neopterin-3’-triphosphate  (Please refer to our reference 8)
11.309(6R,S)-5,6,7,8-Tetrahydro-D-neopterin dihydrochloride
11.314D-Neopterin-3’-monophosphate, lithium salt
11.3157,8-Dihydro-D-neopterin-3’-monophosphate, lithium salt  
11.3203'-Hydroxy-D-sepiapterin
11.3307-Neopterin  
11.340L-Monapterin [L-threo-Neopterin]
11.3457,8-Dihydro-L-monapterin
11.346(6R,S)-5,6,7,8-Tetrahydro-L-monapterin dihydrochloride
11.349D-Monapterin [D-threo-Neopterin]
11.403Pterin-6-carboxylic acid
11.409Pterin-7-carboxylic acid
11.4156-Formylpterin [Pterin-6-aldehyde]
11.4166-Formyl-7,8-dihydropterin
11.418Acetyl-6-formylpterin
11.4206-Hydroxymethylpterin
11.4216-Hydroxymethyl-7,8-dihydropterin hydrochloride
11.4226-Hydroxymethyl-7,8-dihydropterin-diphosphate    (Please refer to our reference 8)
11.423(6R,S)-6-Hydroxymethyl-5,6,7,8-tetrahydropterin dihydrochloride
11.4296-Hydroxymethylpterin-monophosphate 
11.4386-Hydroxymethylpterin-diphosphate, lithium salt  
11.4806-Methylpterin
11.4816-Methyl-7,8-dihydropterin hydrochloride
11.483(6R,S)-6-Methyl-5,6,7,8-tetrahydropterin dihydrochloride
11.5036,7-Dimethylpterin
11.5066,7-Dimethyl-7,8-dihydropterin monohydrochloride
11.5096,7-Dimethyl-5,6,7,8-tetrahydropterin monohydrochloride
11.703Leucopterin
11.713Xanthopterin
11.716Dihydroxanthopterin
11.723Isoxanthopterin
11.903Pterin
11.9067,8-Dihydropterin  (Please refer to our reference 20)
11.9095,6,7,8-Tetrahydropterin dihydrochloride
13.103Lumazine
13.2036-Hydroxylumazine
13.2066-Hydroxy-7,8-dihydrolumazine
13.2207-Hydroxylumazine
16.113Pteroic acid
16.123N10-(Trifluoroacetyl)pteroic acid
16.14010-Formylpteroic acid
16.203Folic acid  
16.2067,8-Dihydrofolic acid
16.208(6S)-5,6,7,8-Tetrahydrofolic acid trihydrochloride  
16.209(6R,S)-5,6,7,8-Tetrahydrofolic acid trihydrochloride 
16.21110-Methylfolic acid
16.21510-Formylfolic acid  
16.21710-Formyl-5,6,7,8-tetrahydrofolic acid  (Please refer to our reference 19)
16.220(6R,S)-5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt 
16.222(6R)-5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt (unnatural calcium folinate)  
16.230(6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic acid chloride
16.233(6R,S)-5-Methyl-5,6-dihydrofolic acid, ammonium salt  
16.235(6R,S)-5-Methyl-5,6,7,8-tetrahydrofolic acid, calcium salt
16.236(6S)-5-Methyl-5,6,7,8-tetrahydrofolic acid, calcium salt
16.243(6R,S)-5-Methyl-5,6,7,8-tetrahydropteroyltri-γ-L-glutamic acid trihydrochloride
16.244(6R,S)-5-Methyl-5,6,7,8-tetrahydropteroyltetra-γ-L-glutamic acid trihydrochloride
16.252Pteroyldi-γ-L-glutamic acid  
16.253Pteroyltri-γ-L-glutamic acid   has been discontinued
16.254Pteroyltetra-γ-L-glutamic acid  
16.255Pteroylpenta-γ-L-glutamic acid  has been discontinued
16.266Pteroylhexa-γ-L-glutamic acid, ammonium salt
16.267Pteroylhepta-γ-L-glutamic acid, ammonium salt  
16.280(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroic acid
16.282(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroyldi-γ-L-glutamic acid, lithium salt has been discontinued
16.283(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroyltri-γ-L-glutamic acid, lithium salt has been discontinued
16.284(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroyltetra-γ-L-glutamic acid, lithium salt
16.285(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroylpenta-γ-L-glutamic acid, lithium salt
16.286(6R,S)-5-Formyl-5,6,7,8-tetrahydropteroylhexa-γ-L-glutamic acid, lithium salt
16.330Aminopterin [4-Aminofolic acid]
16.4034-Amino-10-methylpteroic acid (APA, DAMPA)
16.411Methotrexate  [4-Amino-10-methylpteroyl-γ-L-glutamic acid]
16.4124-Amino-10-methylpteroyldi-γ-L-glutamic acid, ammonium salt [Methotrexate diglutamate]
16.4134-Amino-10-methylpteroyltri-γ-L-glutamic acid, ammonium salt [Methotrexate triglutamate] 
16.4144-Amino-10-methylpteroyltetra-γ-L-glutamic acid, ammonium salt [Methotrexate tetraglutamate] 
16.4154-Amino-10-methylpteroylpenta-γ-L-glutamic acid, ammonium salt [Methotrexate pentaglutamate]
16.4164-Amino-10-methylpteroylhexa-γ-L-glutamic acid, ammonium salt [Methotrexate hexaglutamate]
16.4174-Amino-10-methylpteroylhepta-γ-L-glutamic acid, ammonium salt [Methotrexate heptaglutamate] 
16.5007-Hydroxymethotrexate   
16.701p-Aminobenzoyl-L-glutamic acid
16.702p-Aminobenzoyldi-γ-L-glutamic acid, ammonium salt  
16.703p-Aminobenzoyltri-γ-L-glutamic acid, ammonium salt  
16.704p-Aminobenzoyltetra-γ-L-glutamic acid, ammonium salt  
16.705p-Aminobenzoylpenta-γ-L-glutamic acid, ammonium salt  
16.706p-Aminobenzoylhexa-γ-L-glutamic acid,  ammonium salt 
16.707p-Aminobenzoylhepta-γ-L-glutamic acid, ammonium salt  has been discontinued
16.901Z-Glu-OtBu
16.902Z-Glu2-OtBu3
16.903Z-Glu3-OtBu4  
16.904Z-Glu4-OtBu5  
16.905Z-Glu5-OtBu6  
16.906Z-Glu6-OtBu7  
91.303D-(5-15N)-Neopterin
96.203(5-15N)-Folic acid 
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