艾美捷科技特约代理Everest Biotech公司产品。

Everest Biotech公司成立于2000年，该公司主要生产山羊抗体，针对人类、小鼠、大鼠等物种的一系列重要的抗原。另外，Everest Biotech公司已通过ISO 9001:2015认证 (Certificate number CA14829)，可靠的质量和个性化的服务，使得客户以遍布全球。

所有来自Everest Biotech的抗体均有以下特性
（1） Everest Biotech自主研发生产
（2）全部经过肽亲和纯化以保证最佳的特异性和纯度；
（3）经过免疫原肽的ELISA和WB实验验证;
（4）PhD科学家团队，提供全方位技术支持服务。

Everest Biotech - Experts in antigen affinity purified goat polyclonal antibodies.  

Since 2000, Everest has been producing a catalog containing thousands of goat antibodies against a broad range of human, mouse and rat proteins of biomedical interest.

Everest Biotech's commitment to quality and continuous improvement has been recognised with ISO 9001:2015 accreditation (Certificate number CA14829). The customers can be assured they will receive high quality product and excellent customer service.

按疾病种类分：

Allergy

Autoimmunity

Cancer

Cardiovascular

Genetic Disorders

Infectious

Metabolic

Neuronal

按生物功能分：

Adhesion

Apoptosis and its regulation

Autophagy

Cell Cycle and DNA Repair

Chromatin, Histone and RNA regulation

CNS and PNS

Cytoskeletal elements

Embryogenesis and cell differentiation

GAP, GBP, GEF. GRP, GTPase proteins

Inflammation

lectins

Lipids and Sterols Pathways

Mitochondrial proteins

Protein integrity, maturation and break down

Protein Kinases

Protein Phosphatases and Inhibitors

Receptors

SH2 domain containing proteins

SH3 domain containing proteins

Transcriptional regulators

Transcription factors

Translation and its regulation

Transporters, protein sorting, channels

更多详情请联系 

艾美捷科技有限公司

全国服务热线：400-6800-868

邮箱：sales@amyjet.com

网站：www.amyjet.com

Toronto Research Chemical建立于1982年，致力于为生物医药研发人员提供小分子有机物，库存超过57000种，并通过一系列方法保证标准物质的纯度。

Toronto Research Chemicals, TRC, was founded in 1982 by Dr. David Dime to manufacture and supply researchers in the biomedical fields with specialized complex organic small molecules that were not commercially available. In 1983, the company was incorporated in Ontario as Toronto Research Chemicals Inc. It was initially located at the University of Toronto. As the business expanded, larger facilities were required to accommodate the growth.

Today, Toronto Research Chemicals Inc. employs about 150 full time staff, of which approximately 80 are PHD's, operating in a 65,000 square foot facility. TRC, currently manufactures and distributes in excess of 33,000 products to more than 65 countries.

Toronto Research Chemical的产品涵盖：

Activators; Affinity Chromatography; Agonists; Agro-Products; Aldehyde Labeling Reagents; Aldehydes; Amines; Amino Acids & Derivatives; Anti-virals; Antibiotics; Apoptosis; Benzodiazepines; Biotin Derivatives; Boron Derivatives; Carbohydrates; Catalysts; Charged Bifunctional Reagents; Charged Monofunctional Reagents; Chelating Agents & Ligands; Chiral Reagents; Chromatography Media; Cross Linking Reagents; Crosslinker; CyanineDyes; Detergents; Diagnostics; Dihydropyridine; Dopamines; DrugAnalogues; ElectrophoresisMaterials; Environmental; Enzyme Substrates; Ephedrines; Fatty Acids & Derivatives; Fentanyls; Fluorescent Labels &Indicators; Glucuronides; Glutathione S-Transferase Agents; Glycerols; Glycosidase Inhibitors; Heterocycles; Hydantoins; Impurities; Indole Derivatives; Inhibitors; Inositols; Isotope Labelled Compounds; Labeling and Diagnostics Reagents; Lipids; Lysergic Acid and Derivatives; Maleimide Derivatives; Mercaptans/Thiols; Metabolites; Methadones and Analogues; Miscellaneous Compounds; Morphine Based Alkaloids; MTS & Sulfhydryl Active Compounds; Mutagenesis Research Chemicals; Neurochemicals; Neutral Bifunctional Reagents; Neutral Monofunctional Reagents; Nicotine Derivatives; Nitric Oxide Reagents; Non-nucleoside Reverse Transcriptase; Nucleotides; Oligosaccharides; Opium Alkaloids - Natural and Derivatives; Peptides; Pharmaceuticals; Phenethylamines; Phosphorylating and Phosphitylating Agents; Phosphorylcholine Derivatives; Photoaffinity Labels; Polyethyleneglycol Derivatives; Polymers; Protein Kinase Inhibitors and Activators; Pyridyl Disulfides; Retinoids; Selenium Compounds; Sphingosine Derivatives; Spin Labeling Compounds; Steroids; Sulfonyl Chlorides; Tyrosine Kinase Inhibitors; Wittig Reagents.

更多详情请联系 

艾美捷科技有限公司

全国服务热线：400-6800-868

邮箱：sales@amyjet.com

网站：www.amyjet.com

艾美捷科技代理Gene Tools品牌

Gene Tools是一家生产和销售Morpholino Anti-sense oligos（反义寡核苷酸)的公司，其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成，为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具，已被广泛用于：阻断靶mRNA 翻译 (下调基因）；诱导RNA选择性剪接 (下调或上调基因）；阻断 miRNA；阻断病毒 RNA；阻断 non-coding RNA。

▍Morpholino介绍

Morpholino属于第三代反义寡核苷酸，主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用，目前已经广泛用于发育生物学和细胞学实验中，并取得了非常好的实验效果。

Morpholino以吗啉环类似物为基本骨架，这种独特的结构特性使得Morpholino 具有以下几个特点：

● 与其他类型的反义寡核苷酸相比，Morpholino 能更好地抵抗核酸酶的作用；

● Morpholino 与靶序列结合后通过空间位阻效应发挥作用， 不激活RNaseH，不引起目标基因mRNA 的降解 ；

● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译，针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切，得到不 同的转录本，可以方便地用于目标基因结构域的突变研究；

● 与靶序列结合能力强，可以渗入mRNA 的二级结构， 并且特异性好。

配合Morpholino 的使用，Gene Tools公司开发了相应的递送系统，可以安全、高效地将Morpholino 输送至胞内，因此，Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外，Morpholino 可以标上荧光基团、亲和标签以及活性反应基团，以供不同的研究需要。

▍Gene Tools公司产品介绍

● Custom Morpholino：可以根据目标基因序列定制设计并合成Morpholino，用于体外细胞实验或某些直接显微注射的模型（如斑马鱼、非洲爪蟾胚胎）。

● Vivo-Morpholino：适用于活体动物模型（小鼠，大鼠，狗，灵长类等），细胞培养，器官培养等。通过特殊的末端修饰，提高了其穿透细胞膜进入组织细胞的能力，使得在成年动物（主要是小鼠、大鼠）中进行系统性基因功能研究成为可能。

● Prepared Control Oligos：根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型（小鼠，大鼠，狗，灵长类等），细胞培养，器官培养等。

● Endo-Porter：为了解决Morpholino在体外培养细胞中摄取效率低的问题，Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。